Myokines, or ‘Hope Molecules”, hold the key to improved mental and physical well-being. They are proteins that our muscles release every time they contract- primarily through consistent exercise like biking, walking or swimming, or through weightlifting. Myokines have been shown to have a positive impact on both our mental and physical well-being.
Once released into the blood stream, Myokines get to work physically reducing inflammation, lowering blood sugar, oxidizing fat, increasing muscle strength and improving metabolism. Myokines can also cross the blood-brain barrier to improve our mental health. This means they have a direct, positive impact on one’s mental well-being. Myokines have been proven to reduce depression, lower anxiety and increase one’s resilience to stress. Additionally, Myokines help keep age-related mental decline at bay. Myokines also hold the key to improved memory, motor function and learning, while slowing the progression of sarcopenia. (, Ph.D., M.S., and , M.D., F.A.N.P.A. , 2025, The Journal of Neuropsychiatry and Clinical Neurosciences, Volume 37, Number 1)
Remember, the next time you are feeling low or tired, your body holds the key to improved mental and physical well-being. Take a brisk walk, go for a swim, get to the gym or dance around your room. Each move you make releases Myokines that will help you to feel, move and think better. The results are immediate and can also help your future self. At Say Fitness, we can create challenging, engaging workouts that will help improve your mental and physical health!
The above information is from an article by Dr. Ram Rao, PhD, 2023, Myokines: The Hope Molecule, Apollo Health
